PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32485246-8	2020	Notably, anti-tumor drugs such as kaempferol, beta-elemene and sorafenib upregulate the expression of PTEN to exert their inhibitory effects on bladder cancer cells.	beta-elemene	46-58	phosphatase and tensin homolog	Homo sapiens	102-106	
35069732-0	2022	beta-Elemene Restrains PTEN mRNA Degradation to Restrain the Growth of Lung Cancer Cells via METTL3-Mediated N6 Methyladenosine Modification.	beta-elemene	0-12	phosphatase and tensin homolog	Homo sapiens	23-27	
35069732-11	2022	More importantly, beta-elemene contributed to the augmented PTEN expression via suppressing its m6A modification.	beta-elemene	18-30	phosphatase and tensin homolog	Homo sapiens	60-64	
35069732-12	2022	To sum up, we provided strong clues that beta-elemene promoted PTEN expression to retard lung cancer progression by the regulation of METTL3-mediated m6A modification.	beta-elemene	41-53	phosphatase and tensin homolog	Homo sapiens	63-67	
34026596-8	2021	Similar patterns of beta-elemene-modulated cyclinD1, c-Myc, COX2, MMP2, MMP9, VEGF, PTEN and Notch1 expression were detected in NSCLC cells.	beta-elemene	20-32	phosphatase and tensin homolog	Homo sapiens	84-88	
30333873-0	2018	beta-elemene induced anticancer effect in bladder cancer through upregulation of PTEN and suppression of AKT phosphorylation.	beta-elemene	0-12	phosphatase and tensin homolog	Homo sapiens	81-85	
30333873-9	2018	Subsequent western blot analyses revealed that bladder cancer cells treated with beta-elemene had increased PTEN expression and decreased expression of pAKT.	beta-elemene	81-93	phosphatase and tensin homolog	Homo sapiens	108-112	
30333873-10	2018	Taken together, these results suggest that beta-elemene has an antitumor effect in bladder cancer cells through the upregulation of PTEN and suppression of AKT phosphorylation.	beta-elemene	43-55	phosphatase and tensin homolog	Homo sapiens	132-136	
25562151-8	2014	The PTEN expression under intervention of beta-elemene was significantly increased and Pgp expression under beta-elemene intervention was significantly decreased in both cell lines.	beta-elemene	42-54	phosphatase and tensin homolog	Homo sapiens	4-8	
26279432-3	2015	We also confirmed that beta-elemene could influence MDR-related miRNA expression and regulate the expression of the target genes PTEN and Pgp, which may lead to the reversal of the chemoresistant breast cancer (BCA) cells.	beta-elemene	23-35	phosphatase and tensin homolog	Homo sapiens	129-133	
26279432-10	2015	The PTEN expression affected by beta-elemene was significantly increased, and the Pgp expression affected by beta-elemene was significantly decreased in both cells and exosomes.	beta-elemene	32-44	phosphatase and tensin homolog	Homo sapiens	4-8	
26279432-12	2015	CONCLUSIONS: Drug resistance can be reversed by beta-elemene, which can alter the expression of some MDR-related miRNAs, including PTEN and Pgp in MCF-7/Adr and MCF-7/Doc in cells.	beta-elemene	48-60	phosphatase and tensin homolog	Homo sapiens	131-135	
25562151-9	2014	CONCLUSIONS: beta-elemene could influence MDR related miRNA expression and subsequently regulate the expression of the target genes PTEN and Pgp, which may lead to reduction of the viability of the chemo-resistant breast cancer cells.	beta-elemene	13-25	phosphatase and tensin homolog	Homo sapiens	132-136