PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30422809-0	2019	Antitumor effects of beta-elemene via targeting the phosphorylation of insulin receptor.	beta-elemene	21-33	insulin receptor	Homo sapiens	71-87	
30422809-6	2019	To investigate the mechanisms, we focused on the effects of beta-elemene on IR signaling pathway.	beta-elemene	60-72	insulin receptor	Homo sapiens	76-78	
30422809-8	2019	Further, the phosphorylation of IR was found to be suppressed notably by beta-elemene specifically in tumor cells but not normal hepatocytes.	beta-elemene	73-85	insulin receptor	Homo sapiens	32-34	
30422809-9	2019	In addition, beta-elemene inhibited the growth of ESFT xenografts in vivo, and the phosphorylation of IR and S6 ribosomal protein was significantly repressed in the beta-elemene-treated xenografts.	beta-elemene	165-177	insulin receptor	Homo sapiens	102-104	
30422809-10	2019	These data suggest that beta-elemene targets IR phosphorylation to inhibit the proliferation of tumor cells specifically and enhace the effects of IGF1R inhibitors.	beta-elemene	24-36	insulin receptor	Homo sapiens	45-47