PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26867799-0 2016 beta-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1. beta-elemene 0-12 solute carrier family 31, member 1 Mus musculus 119-139 26867799-4 2016 Western blot and laser scanning confocal microscopy studies indicated that beta-elemene enhanced the sensitivity of HCC cells to oxaliplatin by upregulating copper transporter 1 (CTR1), a major controller of intracellular platinum accumulation. beta-elemene 75-87 solute carrier family 31, member 1 Mus musculus 157-177 26867799-4 2016 Western blot and laser scanning confocal microscopy studies indicated that beta-elemene enhanced the sensitivity of HCC cells to oxaliplatin by upregulating copper transporter 1 (CTR1), a major controller of intracellular platinum accumulation. beta-elemene 75-87 solute carrier family 31, member 1 Mus musculus 179-183 26867799-6 2016 Notably, CTR1 protein expression in xenograft HCC was upregulated in mice who received beta-elemene treatment. beta-elemene 87-99 solute carrier family 31, member 1 Mus musculus 9-13 26867799-7 2016 Taken together, our findings show that beta-elemene can block the reduction of CTR1 resulting from oxaliplatin treatment, and therefore has a synergistic anti-HCC effect with oxaliplatin by enhancing cellular uptake of oxaliplatin. beta-elemene 39-51 solute carrier family 31, member 1 Mus musculus 79-83