PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32308771-10 2020 In vitro, beta-elemene in combination with cetuximab was shown to induce iron-dependent reactive oxygen species (ROS) accumulation, glutathione (GSH) depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1) in KRAS mutant CRC cells. beta-elemene 10-22 solute carrier family 7 member 11 Homo sapiens 293-300