PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32457882-0	2020	beta-Elemene Reverses the Resistance of p53-Deficient Colorectal Cancer Cells to 5-Fluorouracil by Inducing Pro-death Autophagy and Cyclin D3-Dependent Cycle Arrest.	beta-elemene	0-12	cyclin D3	Homo sapiens	132-141	
32457882-9	2020	Determine the role of Cyclin-related protein Cyclin D3 in beta-elemene reversing the resistance of HCT116p53-/- to 5-fluorouracil was detected by overexpression of Cyclin D3.	beta-elemene	58-70	cyclin D3	Homo sapiens	45-54	
32457882-9	2020	Determine the role of Cyclin-related protein Cyclin D3 in beta-elemene reversing the resistance of HCT116p53-/- to 5-fluorouracil was detected by overexpression of Cyclin D3.	beta-elemene	58-70	cyclin D3	Homo sapiens	164-173	
32457882-11	2020	Results: For p53 wildtype colorectal cancer cells, beta-elemene could augment the sensitivity of 5-fluorouracil, for p53-deficient colorectal cancer cells, beta-elemene significantly inhibited cell proliferation in a concentration-dependent manner, and reversed the resistance of HCT116p53-/- to 5-fluorouracil by inducing pro-death autophagy and Cyclin D3-dependent cycle arrest.	beta-elemene	156-168	cyclin D3	Homo sapiens	347-356	
32457882-12	2020	Conclusion: beta-elemene enhances the sensitivity of p53 wild-type cells to 5-fluorouracil, beta-elemene can reverse the resistance of HCT116p53-/- to 5-fluorouracil by inducing pro-death autophagy and Cyclin D3-dependent cycle arrest in p53-deficient colorectal cancer, which will provide a new method for the treatment of p53 deletion colorectal cancer patients.	beta-elemene	92-104	cyclin D3	Homo sapiens	202-211