PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34333105-0 2022 beta-Elemene suppresses hepatocellular carcinoma cell growth via mediating LncRNA HOTAIR / SP1 / PDK1 axis impact of beta-elemene on hepatocellular carcinoma cells growth. beta-elemene 0-12 HOX transcript antisense RNA Homo sapiens 82-88 34333105-9 2022 Additionally, exogenously overexpressed SP1 or HOTAIR prevented beta-Elemene inhibition of the protein-level expression of PDK1, whereas overexpressing PDK1 had no effect on SP1, though it still weakened the inhibition of cell growth and HOTAIR expression by beta-Elemene. beta-elemene 259-271 HOX transcript antisense RNA Homo sapiens 47-53 34333105-9 2022 Additionally, exogenously overexpressed SP1 or HOTAIR prevented beta-Elemene inhibition of the protein-level expression of PDK1, whereas overexpressing PDK1 had no effect on SP1, though it still weakened the inhibition of cell growth and HOTAIR expression by beta-Elemene. beta-elemene 259-271 HOX transcript antisense RNA Homo sapiens 238-244 34333105-10 2022 CONCLUSION: beta-Elemene suppresses HCC cell proliferation via through the regulation of HOTAIR/SP1/PDK1 axis and their interaction. beta-elemene 12-24 HOX transcript antisense RNA Homo sapiens 89-95 34333105-0 2022 beta-Elemene suppresses hepatocellular carcinoma cell growth via mediating LncRNA HOTAIR / SP1 / PDK1 axis impact of beta-elemene on hepatocellular carcinoma cells growth. beta-elemene 117-129 HOX transcript antisense RNA Homo sapiens 82-88 34333105-6 2022 RESULTS: beta-Elemene suppressed HCC cell growth through downregulating HOTAIR, SP1 and PDK1. beta-elemene 9-21 HOX transcript antisense RNA Homo sapiens 72-78 34333105-8 2022 Exogenously overexpressed HOTAIR or SP1 eliminated the suppressive properties of beta-Elemene on them, and both of which regulated PDK1 expression in HCC cells. beta-elemene 81-93 HOX transcript antisense RNA Homo sapiens 26-32 34333105-9 2022 Additionally, exogenously overexpressed SP1 or HOTAIR prevented beta-Elemene inhibition of the protein-level expression of PDK1, whereas overexpressing PDK1 had no effect on SP1, though it still weakened the inhibition of cell growth and HOTAIR expression by beta-Elemene. beta-elemene 64-76 HOX transcript antisense RNA Homo sapiens 47-53