PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30209296-0	2018	Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer.	beta-elemene	114-126	microRNA 155	Homo sapiens	39-47	
30209296-4	2018	Mechanistically, we found that beta-elemene decreased the phosphorylation of signal transducer and activator of transcription 3 (Stat3) and miRNA155-5p mRNA but induced the protein expression of human forkhead box class O (FOXO)3a; the latter two were abrogated in cells with overexpressed Stat3.	beta-elemene	31-43	microRNA 155	Homo sapiens	140-148	
30209296-6	2018	Moreover, beta-elemene increased the mRNA and protein expression levels as well as promoter activity of insulin-like growth factor-binding protein 1 (IGFBP1); this finding was not observed in cells with a silenced FOXO3a gene and miRNA155-5p mimics.	beta-elemene	10-22	microRNA 155	Homo sapiens	230-238	
30209296-9	2018	In summary, our results indicate that beta-elemene increases IGFBP1 gene expression via inactivation of Stat3 followed by a reciprocal interaction between miRNA155-5p and FOXO3a.	beta-elemene	38-50	microRNA 155	Homo sapiens	155-163