PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35628363-3 2022 Previous studies have shown that signaling factors such as JAK2/STAT3, Smad3, and Myd88 play a regulatory role in renal fibrosis, and beta-elemene is a plant-derived sesquiterpenoid organic compound that has been shown to have anti-inflammatory, anti-cancer, and immunomodulatory effects. beta-elemene 134-146 Janus kinase 2 Rattus norvegicus 59-63 35628363-6 2022 Further experiments showed that beta-elemene reduced the expression levels of the above-mentioned fibrosis-related proteins by blocking the phosphorylation of JAK2/STAT3, Smad3, and the expression or up-regulation of MyD88. beta-elemene 32-44 Janus kinase 2 Rattus norvegicus 159-163