PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33223837-0 2020 Down-Regulation of Hypoxia-Inducible Factor-1alpha and Downstream Glucose Transporter Protein-1 Gene by beta-elemene Enhancing the Radiosensitivity of Lung Adenocarcinoma Transplanted Tumor. beta-elemene 104-116 hypoxia inducible factor 1, alpha subunit Mus musculus 19-50 33223837-1 2020 Purpose: To study the effect of beta-elemene on the radiosensitivity of A549 cell xenograft tumor and potential mechanisms by which beta-elemene regulates the expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and glucose transporter protein-1 (GLUT-1). beta-elemene 132-144 hypoxia inducible factor 1, alpha subunit Mus musculus 173-204 33223837-4 2020 The relationship between the radiosensitivity of beta-elemene and the expression of HIF-1alpha and GLUT-1 was analyzed. beta-elemene 49-61 hypoxia inducible factor 1, alpha subunit Mus musculus 84-94 33223837-7 2020 When beta-elemene was used in combination with radiation, the expression of HIF-1alpha and GLUT-1 was significantly decreased, and there was a positive correlation between the two genes. beta-elemene 5-17 hypoxia inducible factor 1, alpha subunit Mus musculus 76-86 33223837-9 2020 The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. beta-elemene 136-148 hypoxia inducible factor 1, alpha subunit Mus musculus 86-96 33223837-9 2020 The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. beta-elemene 136-148 hypoxia inducible factor 1, alpha subunit Mus musculus 202-212