PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29363722-0 2018 Therapeutic effects of beta-elemene via attenuation of the Wnt/beta-catenin signaling pathway in cervical cancer cells. beta-elemene 23-35 catenin beta 1 Homo sapiens 63-75 29737579-6 2018 Expression of key kinases, including Wnt3a, and beta-catenin, were down-regulated by beta-elemene through a miR-191 mechanism. beta-elemene 85-97 catenin beta 1 Homo sapiens 48-60 29737579-7 2018 Moreover, beta-elemene might improve resistance of colorectal carcinoma cells to 5-FU by down-regulating miR-191, thereby inhibiting the Wnt/beta-catenin pathway. beta-elemene 10-22 catenin beta 1 Homo sapiens 141-153 29358311-0 2018 beta-Elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/beta-catenin pathway. beta-elemene 0-12 catenin beta 1 Homo sapiens 121-133 29358311-7 2018 At last, we used canonical Wnt/beta-catenin pathway activator (LiCl) to further ascertain the mechanism of beta-elemene. beta-elemene 107-119 catenin beta 1 Homo sapiens 31-43 29358311-9 2018 beta-Elemene didn"t affect normal human airway fibroblasts; however, it had a dose-responsive inhibitive effect on the proliferation and expression of Wnt3a, non-active GSK-3beta, beta-catenin, alpha-SMA, TGF-beta, and Col-I of human airway granulation fibroblasts. beta-elemene 0-12 catenin beta 1 Homo sapiens 180-192 29358311-12 2018 Thus, beta-elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/beta-catenin pathway. beta-elemene 6-18 catenin beta 1 Homo sapiens 127-139 29363722-11 2018 Western blotting demonstrated that beta-elemene reduced the expression levels of beta-catenin and its downstream target molecule TCF7, thus resulting in reduced levels of their target proteins, including c-Myc, Cyclin D1, Bax and MMP-2 in cervical cancer cells. beta-elemene 35-47 catenin beta 1 Homo sapiens 81-93 29363722-12 2018 The results of the present study suggested that beta-elemene may inhibit cell proliferation and invasion, in addition to inducing apoptosis, via attenuation of the Wnt/beta-catenin signaling pathway in cervical cancer cells. beta-elemene 48-60 catenin beta 1 Homo sapiens 168-180 26563263-13 2015 Inhibiting beta-catenin enhanced the anti-proliferative, EMT-inhibitory and specific marker expression-regulatory effects of beta-elemene. beta-elemene 125-137 catenin beta 1 Homo sapiens 11-23 26563263-0 2015 Reversion of malignant phenotypes of human glioblastoma cells by beta-elemene through beta-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules. beta-elemene 65-77 catenin beta 1 Homo sapiens 86-98 26563263-14 2015 CONCLUSIONS: beta-Elemene reversed malignant phenotypes of human glioblastoma cells through beta-catenin-involved regulation of stemness-, differentiation- and EMT-related molecules. beta-elemene 13-25 catenin beta 1 Homo sapiens 92-104