PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34162690-5	2021	In our study, apically expressed breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) transported atorvastatin, fluvastatin, pitavastatin, and rosuvastatin.	Rosuvastatin Calcium	156-168	ATP binding cassette subfamily B member 1	Homo sapiens	77-91	
16415124-3	2006	The present study was designed to determine whether rosuvastatin is transported by MDR1, MRP2, and BCRP.	Rosuvastatin Calcium	52-64	ATP binding cassette subfamily B member 1	Homo sapiens	83-87	
34162690-5	2021	In our study, apically expressed breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) transported atorvastatin, fluvastatin, pitavastatin, and rosuvastatin.	Rosuvastatin Calcium	156-168	ATP binding cassette subfamily B member 1	Homo sapiens	93-97	
18617601-7	2008	The ATP-dependent uptake of rosuvastatin by human BCRP-expressing membrane vesicles was significantly higher than the uptake by green fluorescent protein-expressing control vesicles, suggesting that MRP2, MDR1, and BCRP can transport rosuvastatin.	Rosuvastatin Calcium	28-40	ATP binding cassette subfamily B member 1	Homo sapiens	205-209	
23469685-0	2013	ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics.	Rosuvastatin Calcium	116-128	ATP binding cassette subfamily B member 1	Homo sapiens	0-5	
23469685-0	2013	ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics.	Rosuvastatin Calcium	116-128	ATP binding cassette subfamily B member 1	Homo sapiens	26-31	
23469685-6	2013	Cav,ss, AUCss and dose-normalized peak plasma concentration (Cmax) and AUC(0-infinity) of single-dose rosuvastatin were significantly related with ABCB1 C1236T, G2677T/A and C3435T polymorphisms and ABCB1 haplotypes.	Rosuvastatin Calcium	102-114	ATP binding cassette subfamily B member 1	Homo sapiens	147-152	
23469685-6	2013	Cav,ss, AUCss and dose-normalized peak plasma concentration (Cmax) and AUC(0-infinity) of single-dose rosuvastatin were significantly related with ABCB1 C1236T, G2677T/A and C3435T polymorphisms and ABCB1 haplotypes.	Rosuvastatin Calcium	102-114	ATP binding cassette subfamily B member 1	Homo sapiens	199-204	
23469685-8	2013	ABCB1 haplotype (1236TT-2677TT-3435TT) had significant influence on dose-normalized pharmacokinetics of single-dose rosuvastatin.	Rosuvastatin Calcium	116-128	ATP binding cassette subfamily B member 1	Homo sapiens	0-5	
23469685-13	2013	We conclude that ABCB1 C1236T, G2677T/A and C3435T polymorphism, ABCB1 haplotypes and ABCG2 c.421C > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics in healthy Chinese volunteers, and potentially affect the efficacy and toxicity of statin therapy.	Rosuvastatin Calcium	155-167	ATP binding cassette subfamily B member 1	Homo sapiens	17-22	
22081364-9	2012	Genetic polymorphisms observed for BCRP, MDR1, and OATP2B1, and IC(50) determined for hERG blocking lead us to propose that some patients may be at risk of rosuvastatin-induced LQTS.	Rosuvastatin Calcium	156-168	ATP binding cassette subfamily B member 1	Homo sapiens	41-45	
21447733-8	2011	Results indicate that atorvastatin, fluvastatin, and rosuvastatin were transported by P-gp, BCRP, and MRP2.	Rosuvastatin Calcium	53-65	ATP binding cassette subfamily B member 1	Homo sapiens	86-90	
21351272-7	2010	Here we evaluate interactions between 4 statins (lovastatin, atorvastatin, fluvastatin and rosuvastatin) and P-gp, at both the molecular level using purified P-gp and at the cellular level using human MDR tumor cells.	Rosuvastatin Calcium	91-103	ATP binding cassette subfamily B member 1	Homo sapiens	109-113	
21351272-10	2010	Finally, fluvastatin and rosuvastatin only interacted with P-gp in vitro at high concentrations and did not inhibit doxorubicin transport in MDR cells.	Rosuvastatin Calcium	25-37	ATP binding cassette subfamily B member 1	Homo sapiens	59-63	
19694740-1	2009	AIMS: This study aimed to investigate possible effects of ABCB1 genotype on fluvastatin, pravastatin, lovastatin, and rosuvastatin pharmacokinetics.	Rosuvastatin Calcium	118-130	ATP binding cassette subfamily B member 1	Homo sapiens	58-63	
18617601-7	2008	The ATP-dependent uptake of rosuvastatin by human BCRP-expressing membrane vesicles was significantly higher than the uptake by green fluorescent protein-expressing control vesicles, suggesting that MRP2, MDR1, and BCRP can transport rosuvastatin.	Rosuvastatin Calcium	234-246	ATP binding cassette subfamily B member 1	Homo sapiens	205-209	
18612079-8	2008	Rosuvastatin efflux at the apical membrane was mediated by MRP2/4 and ABCG2 together with a small contribution from MDR1 or P-glycoprotein.	Rosuvastatin Calcium	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	116-120	
18612079-8	2008	Rosuvastatin efflux at the apical membrane was mediated by MRP2/4 and ABCG2 together with a small contribution from MDR1 or P-glycoprotein.	Rosuvastatin Calcium	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	124-138