PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19948880-12 2010 The messenger RNA expression of TNF-alpha, IL-1beta, IFN-gamma, MCP1, ICAM-1 and ET-1 was increased in DSH, which was attenuated by rosuvastatin treatment. Rosuvastatin Calcium 132-144 interleukin 1 beta Rattus norvegicus 43-51 26633263-7 2016 Moreover, rosuvastatin markedly inhibited microglial activation in LPS-challenged cells by affecting both their morphology and functions as it inhibited LPS-elicited phagocytosis and inhibited pro-inflammatory cytokine (IL-1beta, TNF-alpha) production, concomitantly increasing the level of IL-10, an anti-inflammatory cytokine. Rosuvastatin Calcium 10-22 interleukin 1 beta Rattus norvegicus 220-228 15681303-6 2005 In comparison with vehicle-treated SHRSP, rosuvastatin treatment attenuated the transcription of monocyte chemoattractant protein-1, transforming growth factor-beta1, IL-1beta, and tumor necrosis factor-alpha in the kidney, and of P-selectin in brain vessels and increased the transcription of endothelial nitric oxide synthase mRNA in the aorta. Rosuvastatin Calcium 42-54 interleukin 1 beta Rattus norvegicus 167-175 29525080-6 2018 RESULTS: We found that combined rosuvastatin and resveratrol pretreatment not only significantly decreased the neurologic defective score, cerebral infarct volume, the levels of caspase-3, and Interleukin-1beta (IL-1beta) but also significantly increased the ratios of Bcl-2/Bax and LC3II/LC3I, as well as the level of Becline-1, compared with resveratrol alone or rosuvastatin alone pretreatment group. Rosuvastatin Calcium 32-44 interleukin 1 beta Rattus norvegicus 193-210 29525080-6 2018 RESULTS: We found that combined rosuvastatin and resveratrol pretreatment not only significantly decreased the neurologic defective score, cerebral infarct volume, the levels of caspase-3, and Interleukin-1beta (IL-1beta) but also significantly increased the ratios of Bcl-2/Bax and LC3II/LC3I, as well as the level of Becline-1, compared with resveratrol alone or rosuvastatin alone pretreatment group. Rosuvastatin Calcium 32-44 interleukin 1 beta Rattus norvegicus 212-220 27338064-13 2016 Rosuvastatin treatment reduced the infiltration of inflammatory cells and TNF-alpha and IL-1beta expression. Rosuvastatin Calcium 0-12 interleukin 1 beta Rattus norvegicus 88-96 28637984-6 2017 Although rosuvastatin reduced the levels of IL-1beta, they did not differ significantly between the PR and P groups. Rosuvastatin Calcium 9-21 interleukin 1 beta Rattus norvegicus 44-52 25445360-10 2015 Additionally, the activation of astrocytes, the phosphorylation of extracellular signal-regulated kinase 42/44 (ERK(42/44)) and the expressions of TNFalpha and IL-1beta were inhibited significantly by rosuvastatin. Rosuvastatin Calcium 201-213 interleukin 1 beta Rattus norvegicus 160-168