PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20946880-2 2010 In the present investigation, we analyzed whether treatment with rosuvastatin, an inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, would prevent the increases in inflammatory microglia and IL-6 levels in the brain and plasma of WT and ApoE-/- mice. Rosuvastatin Calcium 65-77 interleukin 6 Mus musculus 223-227 28740344-7 2017 Multiplex ELISA analysis revealed that rosuvastatin treatment reduced the DSS-induced increase of serum IL-2, IL-4, IL-5, IL-6, IL-12 and IL-17, and G-CSF levels. Rosuvastatin Calcium 39-51 interleukin 6 Mus musculus 122-126 28025996-11 2016 Rosuvastatin significantly decreased the expression levels of pro-inflammatry cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-6 and transforming growth factor (TGF)-beta1. Rosuvastatin Calcium 0-12 interleukin 6 Mus musculus 132-150 27316397-7 2016 CONCLUSION: AS attenuated progression of atherosclerosis lesion formation alone or combined with rosuvastatin through anti-inflammatory effect, resulting in down-regulation of TNF-alpha and IL-6, and further down-regulating IL-8 and MCP-1 expressions in aorta of WD fed ApoE(-/-) mice. Rosuvastatin Calcium 97-109 interleukin 6 Mus musculus 190-194 29185103-12 2017 Aspirin, ticagrelor, and rosuvastatin decreased serum IL-1beta and IL-6 levels. Rosuvastatin Calcium 25-37 interleukin 6 Mus musculus 67-71 28622591-7 2017 Administration of rosuvastatin and/or ubiquinone to TRZ-treated mice induced significant increase in tissue GPx, CAT and STAT-3 with significant decrease in serum CK-MB, LDH, troponin I, NT-pro BNP, tissue MDA, TGF-beta1 and IL-6 and improved the histopathological, immunohistochemical, echocardiographic and electron microscopic changes compared to the group that received TRZ alone. Rosuvastatin Calcium 18-30 interleukin 6 Mus musculus 225-229 23276528-8 2013 RESULTS: Rosuvastatin significantly decreased thrombus weight, plasminogen activator inhibitor-1 expression and plasma levels, expression of molecules related to the interleukin-6 pathway, and neutrophil migration into the vein wall. Rosuvastatin Calcium 9-21 interleukin 6 Mus musculus 166-179 22382902-13 2012 Furthermore, treatment with rosuvastatin decreased the expression levels of TNF-alpha (group H, 65.19 +- 7.06 pg/ml; group L, 108.20 +- 5.28 pg/ml; group N, 239.34 +- 11.65 pg/ml) and IL-6 (group H, 14.33 +- 2.15 pg/ml; group L, 19.67 +- 3.04 pg/ml; group N, 40.39 +- 7.17 pg/ml). Rosuvastatin Calcium 28-40 interleukin 6 Mus musculus 184-188 20946880-5 2010 Rosuvastatin treatment resulted in lowered plasma IL-6 levels in WT mice on a HC diet. Rosuvastatin Calcium 0-12 interleukin 6 Mus musculus 50-54