PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33917884-7	2021	Rosuvastatin/Lactobacillus showed prominent anti-inflammatory effects as revealed by the IL-10/IL-12 ratio and the levels of TNF-alpha and IL-6.	Rosuvastatin Calcium	0-12	interleukin 6	Rattus norvegicus	139-143	
23295058-8	2013	Further study revealed that rosuvastatin significantly decreased hepatic mRNA expression of tumour necrosis factor-alpha and interleukin-6, serum alanine aminotransferase levels and hepatic lobular inflammation grade.	Rosuvastatin Calcium	28-40	interleukin 6	Rattus norvegicus	125-138	
33641435-8	2021	Administration of rosuvastatin reduced the increases in expression of NLRP3, ASC, pro-caspase-1, TLR4, and p65 and decreased the contents of TNF-alpha, IL-1beta, IL-18 and IL-6, with a similar effect as MCC950 (NLRP3 inhibitor).	Rosuvastatin Calcium	18-30	interleukin 6	Rattus norvegicus	172-176	
27539098-5	2016	SHR-CRP rats treated with fenofibrate alone (100 mg/kg body weight) or in combination with rosuvastatin (20 mg/kg body weight) vs. SHR-CRP untreated controls showed increased levels of proinflammatory marker IL6, increased concentrations of ALT, AST and ALP, increased oxidative stress in the liver and necrotic changes of the liver.	Rosuvastatin Calcium	91-103	interleukin 6	Rattus norvegicus	208-211	
30519383-11	2018	Rosuvastatin use also resulted in reduction of TNF-alpha, IL-6, and MDA levels.	Rosuvastatin Calcium	0-12	interleukin 6	Rattus norvegicus	58-62	
21915500-10	2011	Rosuvastatin increased the nitric oxide level in the L-name+rosuvastatin-2 group and reduced the interleukin-6 and tumor necrosis factor alpha levels, glomerular macrophage number and albumin:urinary creatinine ratio in the L-name+rosuvastatin-20 and L-name+rosuvastatin-2 groups.	Rosuvastatin Calcium	0-12	interleukin 6	Rattus norvegicus	97-142	
20121625-6	2010	Rosuvastatin pretreatment appears to protect these organs after hepatic I/R injury through the reduction of proinflammatory cytokines (TNF-alpha, IL-6, and MCP-1) and stimulation of anti-inflammatory cytokines (IL-10) production.	Rosuvastatin Calcium	0-12	interleukin 6	Rattus norvegicus	146-150	
19147451-7	2009	Furthermore, rosuvastatin reduced the increased IL-6 level and further elevated IL-10 level in the peri-infarct and remote zones of MI.	Rosuvastatin Calcium	13-25	interleukin 6	Rattus norvegicus	48-52	
34226988-7	2021	Beyond lipid lowering, rosuvastatin treatment reduced total and differential WBC counts in the A and AH groups (p<0.05 to p<0.001), IL-6 level in the AH group (p<0.05), and IL-10 level in all treated groups (p<0.05).	Rosuvastatin Calcium	23-35	interleukin 6	Rattus norvegicus	132-136