PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16859668-13 2006 Western blot analysis demonstrated that raloxifene stimulated p38 MAPK. Raloxifene Hydrochloride 40-50 mitogen-activated protein kinase 14 Homo sapiens 62-65 26648459-9 2016 Furthermore, the stress kinase p38 was increased and EFGR isoforms were decreased by both raloxifene and raloxifene + RL91. Raloxifene Hydrochloride 90-100 mitogen-activated protein kinase 14 Homo sapiens 31-34 26648459-9 2016 Furthermore, the stress kinase p38 was increased and EFGR isoforms were decreased by both raloxifene and raloxifene + RL91. Raloxifene Hydrochloride 105-115 mitogen-activated protein kinase 14 Homo sapiens 31-34 22212320-8 2011 Phosphorylated p38 MAPK and Akt were also increased after raloxifene treatment. Raloxifene Hydrochloride 58-68 mitogen-activated protein kinase 14 Homo sapiens 15-18 16859668-15 2006 p38 MAPK is, at least in part, involved in the relaxant response to raloxifene. Raloxifene Hydrochloride 68-78 mitogen-activated protein kinase 14 Homo sapiens 0-3 12967334-0 2003 Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells. Raloxifene Hydrochloride 13-23 mitogen-activated protein kinase 14 Homo sapiens 55-91 12967334-6 2003 Both E(2) and raloxifene caused rapid, transient phosphorylation and activation of p38 that was not affected by actinomycin D and was blocked by ICI 182,780. Raloxifene Hydrochloride 14-24 mitogen-activated protein kinase 14 Homo sapiens 83-86 12967334-10 2003 We then examined whether E(2) and raloxifene induce apoptosis through a p38 cascade. Raloxifene Hydrochloride 34-44 mitogen-activated protein kinase 14 Homo sapiens 72-75 12967334-13 2003 Our findings suggest that both E(2)- and raloxifene-induced inhibition of VSMC growth is due to induction of apoptosis through a p38 cascade whose activation is mediated by ERalpha via a nongenomic mechanism. Raloxifene Hydrochloride 41-51 mitogen-activated protein kinase 14 Homo sapiens 129-132 16522698-9 2006 Moreover, tamoxifen and raloxifene also increased phosphorylation of p38 MAPK. Raloxifene Hydrochloride 24-34 mitogen-activated protein kinase 14 Homo sapiens 69-72