PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24726471-2	2014	Raloxifene was shown to mediate an effect through the G protein-coupled estrogen receptor 1 (GPER1).	Raloxifene Hydrochloride	0-10	G protein-coupled estrogen receptor 1	Mus musculus	54-91	
28529128-7	2018	Similarly, the clinically used ER-targeting drugs 4OH-tamoxifen, raloxifene, and ICI182,780 (faslodex, fulvestrant ) induced NO formation in part via GPER.	Raloxifene Hydrochloride	65-75	G protein-coupled estrogen receptor 1	Mus musculus	150-154	
24846829-7	2015	Raloxifene also inhibited the hypoxia-induced decrease in Eralpha mRNA expression and attenuated the hypoxia-induced rise in Erbeta and Gpr30 mRNA expression levels.	Raloxifene Hydrochloride	0-10	G protein-coupled estrogen receptor 1	Mus musculus	136-141	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	15-25	G protein-coupled estrogen receptor 1	Mus musculus	56-93	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	15-25	G protein-coupled estrogen receptor 1	Mus musculus	95-100	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	15-25	G protein-coupled estrogen receptor 1	Mus musculus	177-182	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	134-144	G protein-coupled estrogen receptor 1	Mus musculus	56-93	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	134-144	G protein-coupled estrogen receptor 1	Mus musculus	95-100	
27644075-6	2016	Interestingly, raloxifene activity was prevented by the G protein-coupled estrogen receptor 1 (GPER1) antagonist G15, suggesting that raloxifene effects were mainly mediated by GPER1.	Raloxifene Hydrochloride	134-144	G protein-coupled estrogen receptor 1	Mus musculus	177-182	
26708712-5	2016	Accumulating evidence suggests that GPER1 could be implicated in the neuroprotective effects of estrogen, raloxifene and G1 in collaboration with ERalpha.	Raloxifene Hydrochloride	106-116	G protein-coupled estrogen receptor 1	Mus musculus	36-41	
24726471-0	2014	Raloxifene activates G protein-coupled estrogen receptor 1/Akt signaling to protect dopamine neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.	Raloxifene Hydrochloride	0-10	G protein-coupled estrogen receptor 1	Mus musculus	21-58	
24726471-2	2014	Raloxifene was shown to mediate an effect through the G protein-coupled estrogen receptor 1 (GPER1).	Raloxifene Hydrochloride	0-10	G protein-coupled estrogen receptor 1	Mus musculus	93-98	
24726471-3	2014	We investigated if raloxifene neuroprotective effect in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated male mice is mediated through GPER1 by using its antagonist G15.	Raloxifene Hydrochloride	19-29	G protein-coupled estrogen receptor 1	Mus musculus	146-151	
24726471-8	2014	Our results suggest that raloxifene acted through GPER1 to mediate Akt activation, increase Bcl-2 and brain-derived neurotrophic factor levels, and protection of dopaminergic neurons and plasma androgens.	Raloxifene Hydrochloride	25-35	G protein-coupled estrogen receptor 1	Mus musculus	50-55