PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35614039-7 2022 Mechanistic studies here reported confirm the significant affinity of raloxifene for the Spike protein, as predicted by in silico studies, and show that the drug treatment does not directly affect Spike/ACE2 interaction or viral internalization in infected cell lines. Raloxifene Hydrochloride 70-80 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 89-94 35614039-8 2022 Interestingly, raloxifene can counteract Spike-mediated ADAM17 activation in human pulmonary cells, thus providing new insights on its mechanism of action. Raloxifene Hydrochloride 15-25 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 41-46