PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24387618-6 2014 In genotype 1 (G1) patients, the addition of sofosbuvir to peginterferon plus ribavirin yielded sustained virological response rates at week 12 after discontinuation of treatment (SVR12) of about 90% with slightly lower levels in G1b and in patients with cirrhosis, but with no major impact of IL28B genotype, high viral load, body mass index (BMI), alanine aminotransferase (ALT) or race/ethnicity. Sofosbuvir 45-55 glutamic--pyruvic transaminase Homo sapiens 350-374 34728543-8 2021 CONCLUSION: An increase in the baseline level of alanine aminotransferase was found to play a role in the reduction in the quality of life of patients with chronic hepatitis C who had undergone ledipasvir/sofosbuvir therapy. Sofosbuvir 205-215 glutamic--pyruvic transaminase Homo sapiens 49-73