PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34978808-6	2022	Also, Sal downregulated the Bcl-2, MMP-2, MMP-9, PI3K, and AKT and upregulated BAX proteins.	rhodioloside	6-9	matrix metallopeptidase 2	Homo sapiens	35-40	
29901185-0	2018	Salidroside inhibits migration, invasion and angiogenesis of MDA-MB 231 TNBC cells by regulating EGFR/Jak2/STAT3 signaling via MMP2.	rhodioloside	0-11	matrix metallopeptidase 2	Homo sapiens	127-131	
31432697-7	2019	Salidroside inhibited GC cells proliferation, migration, invasion and promoted apoptosis, which coupled with the down-regulation of p21, Bcl-2, MMP2, RhoA, p-ROCK1, Vimentin and the up-regulations of CyclinD1, Bax, cleaved caspases.	rhodioloside	0-11	matrix metallopeptidase 2	Homo sapiens	144-148	
31120636-8	2019	We further illustrated that salidroside significantly inhibited expressions of MMP2 and MMP9 at mRNA and protein levels and the phosphorylation activation of JAK2/STAT3 in WRO cells.	rhodioloside	28-39	matrix metallopeptidase 2	Homo sapiens	79-83	
30552692-5	2019	Salidroside markedly attenuated the PDGF-induced production of matrix metalloproteinase 2 (MMP-2) and MMP-9 in ASMCs.	rhodioloside	0-11	matrix metallopeptidase 2	Homo sapiens	63-89	
30552692-5	2019	Salidroside markedly attenuated the PDGF-induced production of matrix metalloproteinase 2 (MMP-2) and MMP-9 in ASMCs.	rhodioloside	0-11	matrix metallopeptidase 2	Homo sapiens	91-96	
30822424-9	2019	Meanwhile, down-regulation of Cyclin D1, MMP-2 and Vimentin, up-regulations of p53 and p21, as well as cleavage of caspase-3 and -9 were observed in Salidroside-treated cell.	rhodioloside	149-160	matrix metallopeptidase 2	Homo sapiens	41-46	
29901185-9	2018	An electrophoretic mobility shift assay also demonstrated that salidroside may inhibit the DNA-binding activity of STAT3, preventing STAT3 from binding to a novel binding site of the MMP2 gene promoter.	rhodioloside	63-74	matrix metallopeptidase 2	Homo sapiens	183-187	
21978886-4	2012	The results indicated that salidroside significantly reduced wound closure areas of HT1080 cells, inhibited HT1080 cells invasion into Matrigel-coated membranes, suppressed matrix metalloproteinases (MMP-2 and MMP-9) activity, and increased tissue inhibitor of metalloproteinase-2 (TIMP-2) expression in a dose-dependent manner in HT1080 cells.	rhodioloside	27-38	matrix metallopeptidase 2	Homo sapiens	200-205	
29749547-10	2018	The results indicated that salidroside significantly suppressed cell proliferation and colony formation, inhibited cell migration and invasion, increased E-cadherin expression and decreased N-cadherin, MMP-2 and MMP-9 expression.	rhodioloside	27-38	matrix metallopeptidase 2	Homo sapiens	202-207