PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26231702-9	2015	RESULTS: The cell culture studies revealed that esomeprazole controls inflammation by suppressing the expression of pro-inflammatory molecules including vascular cell adhesion molecule-1, inducible nitric oxide synthase, tumor necrosis factor-alpha (TNF-alpha) and interleukins (IL-1beta and IL-6).	Esomeprazole	48-60	tumor necrosis factor	Homo sapiens	221-248	
29466360-8	2018	We examined the ability of metformin + esomeprazole to rescue TNF-alpha induced vascular cell adhesion molecule-1 (VCAM-1) and Endothelin-1 (ET-1) expression, leukocyte adhesion (markers of endothelial dysfunction).	Esomeprazole	39-51	tumor necrosis factor	Homo sapiens	62-71	
29466360-11	2018	The low-dose combination of metformin + esomeprazole additively reduced TNF-alpha-induced VCAM-1 mRNA, but not VCAM-1 protein expression.	Esomeprazole	40-52	tumor necrosis factor	Homo sapiens	72-81	
34011367-5	2021	METHODS: We stimulated oxidative stress, pro-inflammatory and profibrotic phenotypes in primary human lung epithelial cells and fibroblasts upon treatment with bleomycin or transforming growth factor beta (TGFbeta) and assessed the effect of a prototype PPI, esomeprazole, in regulating these processes.	Esomeprazole	259-271	tumor necrosis factor	Homo sapiens	173-204	
32758704-9	2020	Together, esomeprazole and sulfasalazine additively reduced TNF-alpha-induced VCAM and ET-1 mRNA expression, and monocyte adhesion to endothelial cells.	Esomeprazole	10-22	tumor necrosis factor	Homo sapiens	60-69	
26231702-9	2015	RESULTS: The cell culture studies revealed that esomeprazole controls inflammation by suppressing the expression of pro-inflammatory molecules including vascular cell adhesion molecule-1, inducible nitric oxide synthase, tumor necrosis factor-alpha (TNF-alpha) and interleukins (IL-1beta and IL-6).	Esomeprazole	48-60	tumor necrosis factor	Homo sapiens	250-259