PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32866455-5 2020 Our results were conclusive and showed that both the racemic form, omeprazole and its pure S-enantiomer, esomeprazole, acted as potent mixed-competitive inhibitor of human ChAT with a global inhibition constant (Ki) of 88 nM (95%CI: 10-167nM) for esomeprazole and 178nM (95%CI: 140-230nM) for the racemic drug omeprazole. Esomeprazole 105-117 choline O-acetyltransferase Homo sapiens 172-176 32866455-5 2020 Our results were conclusive and showed that both the racemic form, omeprazole and its pure S-enantiomer, esomeprazole, acted as potent mixed-competitive inhibitor of human ChAT with a global inhibition constant (Ki) of 88 nM (95%CI: 10-167nM) for esomeprazole and 178nM (95%CI: 140-230nM) for the racemic drug omeprazole. Esomeprazole 247-259 choline O-acetyltransferase Homo sapiens 172-176