PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31142283-2 2019 However, the difference of effectiveness in reducing HCC occurrence between tenofovir (TDF) and enticavir (ETV), two first-line NAs drugs, is still little known. Tenofovir 76-85 HCC Homo sapiens 53-56 31142283-3 2019 This meta analysis aims to assess the efficacy in reducing incidence of HCC comparing tenofovir monotherapy with entecavir monotherapy among chronic hepatitis B (CHB) patients by analyzing their long-term clinical outcomes. Tenofovir 86-95 HCC Homo sapiens 72-75 31142283-9 2019 CONCLUSION: There is a better effect of tenofovir in reducing HCC incidence than entecavir, which indicates tenofovir should be used more widely while treating chronic hepatitis B patients. Tenofovir 40-49 HCC Homo sapiens 62-65 31142283-9 2019 CONCLUSION: There is a better effect of tenofovir in reducing HCC incidence than entecavir, which indicates tenofovir should be used more widely while treating chronic hepatitis B patients. Tenofovir 108-117 HCC Homo sapiens 62-65 30267080-3 2019 Objective: To compare entecavir and tenofovir in terms of the risk of HCC and death or liver transplant in patients with CHB infection. Tenofovir 36-45 HCC Homo sapiens 70-73 30267080-10 2019 In the population cohort, the annual incidence rate of HCC was significantly lower in the tenofovir group (0.64 per 100 person-years [PY]) than in the entecavir group (1.06 per 100 PY). Tenofovir 90-99 HCC Homo sapiens 55-58 30267080-11 2019 By multivariable-adjusted analysis, tenofovir therapy was associated with a significantly lower risk of HCC (hazard ratio [HR], 0.61; 95% CI, 0.54-0.70) and all-cause mortality or transplant (HR, 0.77; 95% CI, 0.65-0.92) compared with entecavir. Tenofovir 36-45 HCC Homo sapiens 104-107 30267080-12 2019 The tenofovir group also showed a significantly lower risk of HCC in the 10 923-pair propensity score-matched population cohort (HR, 0.62; 95% CI, 0.54-0.70) and 869-pair propensity score-matched hospital cohort (HR, 0.68; 95% CI, 0.46-0.99) compared with the entecavir group. Tenofovir 4-13 HCC Homo sapiens 62-65 30267080-13 2019 Conclusions and Relevance: This study suggests that tenofovir treatment was associated with a significantly lower risk of HCC compared with entecavir treatment in a population-based cohort of adults with CHB; these findings were validated in a hospital cohort. Tenofovir 52-61 HCC Homo sapiens 122-125 30181772-0 2018 Tenofovir disoproxil fumarate reduce incidence of HCC development in CHB-patients with compensated cirrhosis. Tenofovir 0-29 HCC Homo sapiens 50-53 30181772-9 2018 The cumulative probability of HCC development in TDF-contained group were significantly lower than it in non-TDF-contained group (p < 0.05). Tenofovir 49-52 HCC Homo sapiens 30-33 30181772-9 2018 The cumulative probability of HCC development in TDF-contained group were significantly lower than it in non-TDF-contained group (p < 0.05). Tenofovir 109-112 HCC Homo sapiens 30-33