PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29890415-7	2018	Notably, treatment with montelukast attenuated IL-1beta-induced phosphorylation of IkappaBalpha, IkappaBalpha degradation, nuclear translocation of p65 and NF-kappaB activity to express a luciferase reporter gene in FLSs.	montelukast	24-35	RELA proto-oncogene, NF-kB subunit	Homo sapiens	148-151	
27312202-10	2016	RESULTS: Montelukast suppressed TLR-mediated TNF-alpha expression via the NFkappaB-p65 and mitogen-activated protein kinase (MAPK)-JNK pathway, and enhanced TLR-mediated IL-10 expression via the MAPK-p38 pathway and epigenetic regulation by histone H3 acetylation.	montelukast	9-20	RELA proto-oncogene, NF-kB subunit	Homo sapiens	74-86	
27325144-11	2018	In western blot analysis, montelukast was able to suppress LPS-induced MAPK-phospho-p38 and NF-kappaB-phospho-p65 expression.	montelukast	26-37	RELA proto-oncogene, NF-kB subunit	Homo sapiens	110-113	
27325144-12	2018	CONCLUSION: Montelukast suppressed LPS-induced M2-related cytokines and chemokines in alternatively activated macrophages, and the effects might be mediated through the MAPK-p38 and NF-kappaB-p65 pathways.	montelukast	12-23	RELA proto-oncogene, NF-kB subunit	Homo sapiens	192-195	
18325031-0	2008	Montelukast inhibits tumour necrosis factor-alpha-mediated interleukin-8 expression through inhibition of nuclear factor-kappaB p65-associated histone acetyltransferase activity.	montelukast	0-11	RELA proto-oncogene, NF-kB subunit	Homo sapiens	128-131	
18325031-11	2008	Montelukast did not affect NF-kappaB p65 activation as measured by DNA binding but suppressed NF-kappaB p65-associated HAT activity.	montelukast	0-11	RELA proto-oncogene, NF-kB subunit	Homo sapiens	104-107	
18325031-12	2008	CONCLUSION: Montelukast inhibits TNF-alpha-stimulated IL-8 expression through changes in NF-kappaB p65-associated HAT activity.	montelukast	12-23	RELA proto-oncogene, NF-kB subunit	Homo sapiens	99-102