PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30949053-5 2019 In contrast, only montelukast and zafirlukast activated PPARgamma in the reporter gene assay with EC50 values of 1.17 muM (21.9% max. montelukast 18-29 peroxisome proliferator activated receptor gamma Homo sapiens 56-65 30949053-12 2019 In addition, we found that montelukast and zafirlukast display antagonistic activities concerning recruitment of the PPARgamma cofactor CBP upon ligand binding suggesting that both compounds act as PPARgamma modulators. montelukast 27-38 peroxisome proliferator activated receptor gamma Homo sapiens 117-126 30949053-12 2019 In addition, we found that montelukast and zafirlukast display antagonistic activities concerning recruitment of the PPARgamma cofactor CBP upon ligand binding suggesting that both compounds act as PPARgamma modulators. montelukast 27-38 peroxisome proliferator activated receptor gamma Homo sapiens 198-207