PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25441945-8	2014	Moreover, we described for the first time the binding mode of TZDs in the binding site of FFAR1.	Thiazolidinediones	62-66	free fatty acid receptor 1	Homo sapiens	90-95	
26774923-0	2016	Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARgamma/FFAR1 dual agonists.	Thiazolidinediones	54-72	free fatty acid receptor 1	Homo sapiens	86-91	
26774923-6	2016	It has been reported that some thiazolidinediones (TZDs) activate FFAR1 with micromolar potency.	Thiazolidinediones	31-49	free fatty acid receptor 1	Homo sapiens	66-71	
33100202-8	2021	Most of the small molecule FFAR1/GPR40 agonists developed were aryl alkanoic acid derivatives (such as phenylpropionic acids, phenylacetic acids, phenoxyacetic acids and benzofuran acetic acid derivatives) and thiazolidinediones.	Thiazolidinediones	210-228	free fatty acid receptor 1	Homo sapiens	27-32	
25441945-0	2014	Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of receptor activation.	Thiazolidinediones	106-124	free fatty acid receptor 1	Homo sapiens	130-135	
25441945-4	2014	It was reported that some thiazolidinediones (TZDs), the best studied PPARgamma agonists, are also able to stimulate FFAR1 in a dose-dependent manner.	Thiazolidinediones	26-44	free fatty acid receptor 1	Homo sapiens	117-122	
25441945-4	2014	It was reported that some thiazolidinediones (TZDs), the best studied PPARgamma agonists, are also able to stimulate FFAR1 in a dose-dependent manner.	Thiazolidinediones	46-50	free fatty acid receptor 1	Homo sapiens	117-122	
19398560-2	2009	However, a range of selective, small molecule ligands have recently been developed as tool compounds to explore the therapeutic potential of this receptor, whereas clinically employed thiazolidinedione "glitazone" drugs are also agonists at FFA1.	Thiazolidinediones	203-212	free fatty acid receptor 1	Homo sapiens	241-245	
34133753-0	2021	Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC).	Thiazolidinediones	0-18	free fatty acid receptor 1	Homo sapiens	65-70	
34133753-0	2021	Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC).	Thiazolidinediones	20-24	free fatty acid receptor 1	Homo sapiens	65-70	
19346435-0	2009	Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.	Thiazolidinediones	0-18	free fatty acid receptor 1	Homo sapiens	88-93	
17987108-1	2007	BACKGROUND: The FFAR1 receptor is expressed mainly in pancreatic beta cells and is activated by medium to long chain free fatty acids (FFAs), as well as by thiazolidinediones, resulting in elevated Ca(2+) concentrations and promotion of insulin secretion.	Thiazolidinediones	156-174	free fatty acid receptor 1	Homo sapiens	16-21