PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31274831-12	2020	In HPDE cells subjected to oxidative stress olaparib (1 muM) inhibited PARP activity, protected against the loss of cell viability and prevented the loss of cellular NAD levels.	olaparib	44-52	latexin	Homo sapiens	56-59	
31071432-17	2019	In in vitro experiments in U937 cells subjected to oxidative stress, olaparib (1-100 muM) inhibited PARP activity, protected against the loss of cell viability, preserved NAD+ levels and improved cellular bioenergetics.	olaparib	69-77	latexin	Homo sapiens	85-88	
28657402-8	2018	In a further study, olaparib (2-200 muM) functioned as a time-dependent inhibitor of CYP3A4/5 (KI, 72.2 muM and Kinact, 0.0675 min-1).	olaparib	20-28	latexin	Homo sapiens	36-39	
28657402-8	2018	In a further study, olaparib (2-200 muM) functioned as a time-dependent inhibitor of CYP3A4/5 (KI, 72.2 muM and Kinact, 0.0675 min-1).	olaparib	20-28	latexin	Homo sapiens	104-107	
28657402-9	2018	Assessment of the CYP induction potential of olaparib (0.061-44 muM) showed minor concentration-related increases in CYP1A2 and more marked increases in CYP2B6 and CYP3A4 mRNA, compared with positive control activity; however, no significant change in CYP3A4/5 enzyme activity was observed.	olaparib	45-53	latexin	Homo sapiens	64-67	
29064327-8	2017	In vitro assay, the half maximal inhibitory concentration of olaparib in HCC1937-APE1-KO was significantly increased (17.22 vs 91.85 muM) compared to the wild type.	olaparib	61-69	latexin	Homo sapiens	133-136	
29064327-10	2017	HCC1937 resulted in more mitotic G2/M arrest and increased apoptosis rate after treatment with 40 muM of olaparib, while HCC1937-APE1-KO did not change significantly.	olaparib	105-113	latexin	Homo sapiens	98-101	
29064327-11	2017	When HCC1937 was treated with different concentrations of olaparib, it was found that APE1 expression decreased more significantly at 15 muM of olaparib was.	olaparib	58-66	latexin	Homo sapiens	137-140	
29064327-11	2017	When HCC1937 was treated with different concentrations of olaparib, it was found that APE1 expression decreased more significantly at 15 muM of olaparib was.	olaparib	144-152	latexin	Homo sapiens	137-140	
22524618-8	2012	RESULTS: A radiosensitizing effect of olaparib was seen even at 0.01 muM.	olaparib	38-46	latexin	Homo sapiens	69-72	
22524618-12	2012	This sensitizing effect was seen at low concentrations of olaparib such as 0.01 muM, and its sensitizing effect was the same at both 0.01 muM and 1 muM.	olaparib	58-66	latexin	Homo sapiens	80-83