PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34663950-4 2021 Multivariate analysis of patients with relapsed platinum-sensitive ovarian cancer from the randomised, placebo-controlled Phase II olaparib maintenance Study19 showed SLFN11 tumour levels associated with sensitivity to olaparib. olaparib 131-139 schlafen family member 11 Homo sapiens 167-173 34663950-4 2021 Multivariate analysis of patients with relapsed platinum-sensitive ovarian cancer from the randomised, placebo-controlled Phase II olaparib maintenance Study19 showed SLFN11 tumour levels associated with sensitivity to olaparib. olaparib 219-227 schlafen family member 11 Homo sapiens 167-173 31490091-8 2019 Radiosensitization by IC87361 and olaparib was significantly enhanced under acute anoxia and chronic hypoxia.Conclusions: The DNA-PK inhibitors KU57788 and IC87361 are more effective radiosensitizers than the PARP-1 inhibitors olaparib and veliparib at non-cytotoxic concentrations in HNSCC cell cultures and their activity is enhanced by SLFN11 and hypoxia. olaparib 34-42 schlafen family member 11 Homo sapiens 339-345 35511434-8 2022 SLFN11 overexpression in GR-CDXL4 led to olaparib sensitivity and was in coherence with neuroendocrine marker expression in patient tumor biopsy, suggesting a predictive value of SLFN11 in NSCLC histological transformation into SCLC. olaparib 41-49 schlafen family member 11 Homo sapiens 0-6 32279088-12 2020 CONCLUSION: We show high PARP1 and SLFN11 expression in DSRCT tumor material and antitumor effects following olaparib and TMZ combination treatment in a preclinical DSRCT model. olaparib 109-117 schlafen family member 11 Homo sapiens 35-41