PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33237350-8 2020 Western blot, quantitative RT-PCR and next-generation sequencing transcriptomic analyses were performed to assess the expression levels of amino acid transporters (including LAT1 and ASCT2, which have been implicated for Fluciclovine uptake). fluciclovine F-18 221-233 solute carrier family 7 member 5 Homo sapiens 174-178 33237350-12 2020 We studied the expression of amino acid transporters (AATs) for 18F-Fluciclovine, namely LAT1 (SLC7A5 and SLC3A2) and ASCT2 (SLC1A5). fluciclovine F-18 64-80 solute carrier family 7 member 5 Homo sapiens 95-101 31283597-2 2019 As an amino acid-based radiotracer transported by LAT-1 and ASCT-2 transporters, fluciclovine exploits the up-regulation of amino acid transporters in malignant cells. fluciclovine F-18 81-93 solute carrier family 7 member 5 Homo sapiens 50-55 32956127-3 2021 18F-fluciclovine uptake is mediated by amino acid transporters, primarily alanine-serine-cysteine transporter 2 and l-type amino acid transporter 1, previously demonstrated to be expressed on thymic carcinomas. fluciclovine F-18 4-16 solute carrier family 7 member 5 Homo sapiens 116-147 32395349-5 2020 First, 18F-fluciclovine is a radiolabeled synthetic amino acid targeting the amino acid transporters ASCT2 and LAT1, which are ubiquitous throughout the body, but overexpressed in prostate cancer. fluciclovine F-18 7-23 solute carrier family 7 member 5 Homo sapiens 111-115 31152256-0 2019 Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer. fluciclovine F-18 71-87 solute carrier family 7 member 5 Homo sapiens 164-195 31152256-0 2019 Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer. fluciclovine F-18 71-87 solute carrier family 7 member 5 Homo sapiens 197-201 31152256-1 2019 PURPOSE: To evaluate the expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter1 (LAT1) in prostate cancer (PCa) and their impact on uptake of 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) which is approved for the detection of recurrent PCa. fluciclovine F-18 233-249 solute carrier family 7 member 5 Homo sapiens 121-125 31152256-12 2019 The uptake of 18F-fluciclovine correlated significantly with LAT1 expression (rho = 0.39, p = 0.01, for SUVmax at 2 min and rho = 0.39, p = 0.01 for VT). fluciclovine F-18 14-30 solute carrier family 7 member 5 Homo sapiens 61-65 31152256-14 2019 CONCLUSIONS: Our findings suggest that LAT1 is moderately associated with the transport of 18F-fluciclovine in local PCa not exposed to hormonal therapy. fluciclovine F-18 91-107 solute carrier family 7 member 5 Homo sapiens 39-43