PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29409752-4 2018 Herein, we report the design of receptor-interacting protein kinase 2 (RIPK2) inhibitors based on pan-kinase inhibitor regorafenib that aim to engage basic activation loop residues Lys169 or Arg171. regorafenib 119-130 receptor interacting serine/threonine kinase 2 Homo sapiens 32-69 26320862-3 2015 The most potent RIPK2 inhibitors were the US Food and Drug Administration-approved drugs ponatinib and regorafenib. regorafenib 103-114 receptor interacting serine/threonine kinase 2 Homo sapiens 16-21 29409752-4 2018 Herein, we report the design of receptor-interacting protein kinase 2 (RIPK2) inhibitors based on pan-kinase inhibitor regorafenib that aim to engage basic activation loop residues Lys169 or Arg171. regorafenib 119-130 receptor interacting serine/threonine kinase 2 Homo sapiens 71-76