PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28479358-8	2017	The present findings thus indicate that P-glycoprotein and BCRP are involved in the accumulation of regorafenib and its active metabolites in the skin, by affecting either their systemic exposure or their plasma distribution in the circulating blood.	regorafenib	100-111	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	59-63	
25563977-0	2015	Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1).	regorafenib	33-44	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	96-100	
25563977-0	2015	Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1).	regorafenib	33-44	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	101-106	
25563977-3	2015	METHODS: We used in vitro transport assays to assess human (h)ABCB1- or hABCG2- or murine (m)Abcg2-mediated active transport at high and low concentrations of regorafenib.	regorafenib	159-170	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	93-98	
25563977-6	2015	Abcg2 and to a lesser extent Abcb1a/1b limited brain and testis accumulation of regorafenib and metabolite M2 (brain only) in mice.	regorafenib	80-91	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	0-5	
25563977-9	2015	CONCLUSIONS: Brain and testis accumulation of regorafenib and brain accumulation of metabolite M2 are restricted by Abcg2 and Abcb1a/1b.	regorafenib	46-57	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	116-121	
28479358-0	2017	Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites.	regorafenib	136-147	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	51-83	
28479358-2	2017	The purpose of this study is to clarify possible involvement of P-glycoprotein and breast cancer resistance protein (BCRP) in the dermal accumulation of regorafenib and its active metabolites M-2 and M-5.	regorafenib	153-164	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	83-115	
28479358-2	2017	The purpose of this study is to clarify possible involvement of P-glycoprotein and breast cancer resistance protein (BCRP) in the dermal accumulation of regorafenib and its active metabolites M-2 and M-5.	regorafenib	153-164	ATP binding cassette subfamily G member 2 (Junior blood group)	Mus musculus	117-121