PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33224274-18	2020	In addition, SMAD4 mutation and TGF-beta pathway were associated with worse PFS after regorafenib.	regorafenib	86-97	SMAD family member 4	Homo sapiens	13-18	
33224274-20	2020	In addition, SMAD4 mutation and the TGF-beta pathway were associated with worse PFS after regorafenib.	regorafenib	90-101	SMAD family member 4	Homo sapiens	13-18	
29211816-11	2017	Conversely, GAS6 amplification and SMAD4 mutation, detected in two long responder patients, might suggest a role of epithelial-mesenchymal transition phenotype in regorafenib response.	regorafenib	163-174	SMAD family member 4	Homo sapiens	35-40