PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30940655-8	2019	By targeting the RET-Src axis, regorafenib potently inhibited JAK1/2-STAT1 and MAPK signaling and subsequently attenuated the IFNgamma-induced PD-L1 and IDO1 expression without affecting MHC-I expression much.	regorafenib	31-42	signal transducer and activator of transcription 1	Homo sapiens	69-74	
34458148-5	2021	Furthermore, we found that regorafenib had an activating effect on signal transducers and activators of transcription 1 (STAT1), and that regorafenib-induced HLA-I expression was dependent on the augmented IFNgamma/STAT1 signaling pathway.	regorafenib	27-38	signal transducer and activator of transcription 1	Homo sapiens	67-119	
34458148-5	2021	Furthermore, we found that regorafenib had an activating effect on signal transducers and activators of transcription 1 (STAT1), and that regorafenib-induced HLA-I expression was dependent on the augmented IFNgamma/STAT1 signaling pathway.	regorafenib	27-38	signal transducer and activator of transcription 1	Homo sapiens	121-126	
34458148-5	2021	Furthermore, we found that regorafenib had an activating effect on signal transducers and activators of transcription 1 (STAT1), and that regorafenib-induced HLA-I expression was dependent on the augmented IFNgamma/STAT1 signaling pathway.	regorafenib	27-38	signal transducer and activator of transcription 1	Homo sapiens	215-220	
34458148-5	2021	Furthermore, we found that regorafenib had an activating effect on signal transducers and activators of transcription 1 (STAT1), and that regorafenib-induced HLA-I expression was dependent on the augmented IFNgamma/STAT1 signaling pathway.	regorafenib	138-149	signal transducer and activator of transcription 1	Homo sapiens	215-220	
34458148-7	2021	Given that regorafenib directly inhibits Raf/MEK/ERK signaling, the downregulation of the MEK/ERK pathway appears to be one of the mechanisms by which regorafenib promotes STAT1 activation.	regorafenib	11-22	signal transducer and activator of transcription 1	Homo sapiens	172-177	
34458148-7	2021	Given that regorafenib directly inhibits Raf/MEK/ERK signaling, the downregulation of the MEK/ERK pathway appears to be one of the mechanisms by which regorafenib promotes STAT1 activation.	regorafenib	151-162	signal transducer and activator of transcription 1	Homo sapiens	172-177