PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17360008-0	2007	Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF.	Lacosamide	29-39	tumor necrosis factor	Rattus norvegicus	82-85	
30118739-6	2018	Treatment with PGB or LCM restored the sciatic nerve content of the depleted total antioxidant capacity (TAC) and nerve growth factor (NGF), and lessened the elevated contents of nuclear factor kappa B p65 (NF-kB p65), tumor necrosis factor-alpha (TNF-alpha), and active caspase-3.	Lacosamide	22-25	tumor necrosis factor	Rattus norvegicus	219-246	
30118739-6	2018	Treatment with PGB or LCM restored the sciatic nerve content of the depleted total antioxidant capacity (TAC) and nerve growth factor (NGF), and lessened the elevated contents of nuclear factor kappa B p65 (NF-kB p65), tumor necrosis factor-alpha (TNF-alpha), and active caspase-3.	Lacosamide	22-25	tumor necrosis factor	Rattus norvegicus	248-257	
25916937-2	2015	The aim of this study is to investigate the potential anti-inflammatory and lipid-peroxidation inhibiting activities of lacosamide by measuring tumour necrotizing factor-alpha (TNF-alpha), C-reactive protein (CRP), malondialdehyde (MDA) and white blood cells (WBC) using electroneuromyography (ENMG) in rats with sepsis-induced critical illness neuropathy (SICIN).	Lacosamide	120-130	tumor necrosis factor	Rattus norvegicus	177-186	
25916937-7	2015	When CLP, CLP+lacosamide 20 mg/kg and CLP+lacosamide 40 mg/kg groups were compared, plasma levels of TNF-alpha and MDA were significantly higher in the untreated CLP group (F = 12.74, P < 0.0001), (F = 19.43, P < 0.05).	Lacosamide	42-52	tumor necrosis factor	Rattus norvegicus	101-110	
33925082-7	2021	Lacosamide treatment after SE mitigated the increased levels of IL-1beta and TNF-alpha in the hippocampus and exerted strong neuroprotection both in the dorsal and ventral hippocampus, basolateral amygdala, and partially in the piriform cortex.	Lacosamide	0-10	tumor necrosis factor	Rattus norvegicus	77-86