PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18378801-7 2008 The estimated IC(50) values for inhibition by lacosamide of Na(v)1.7-, Na(v)1.3-, and Na(v)1.8-type channels following prolonged inactivation were 182, 415, and 16 microM, respectively. Lacosamide 46-56 immunoglobulin lambda variable 2-23 Homo sapiens 60-68 18378801-8 2008 Na(v)1.7-, Na(v)1.3-, and Na(v)1.8-type channels in the resting state were 221-, 123-, and 257-fold less sensitive, respectively, to lacosamide than inactivated channels. Lacosamide 133-143 immunoglobulin lambda variable 2-23 Homo sapiens 0-8