PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33599301-0 2021 Use of Real-World Data and Pharmacometric Modeling in Support of Lacosamide Dosing in Pediatric Patients Under Four Years of Age. Lacosamide 65-75 renin binding protein Homo sapiens 125-128 33599301-5 2021 Based on the developed population pharmacokinetic model, simulations were performed in virtual pediatric patients to explore age-associated dose requirements to match lacosamide exposure in patient groups of different age with the exposure achieved in children >=4 year of age with the weight-based dosing recommendations provided by the FDA. Lacosamide 167-177 renin binding protein Homo sapiens 125-128