PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25931268-0 2015 Lacosamide reduces HDAC levels in the brain and improves memory: Potential for treatment of Alzheimer"s disease. Lacosamide 0-10 histone deacetylase 9 Homo sapiens 19-23 25931268-1 2015 Lacosamide, a histone deacetylase (HDAC) inhibitor, has been approved for the treatment of epilepsy. Lacosamide 0-10 histone deacetylase 9 Homo sapiens 14-33 25931268-1 2015 Lacosamide, a histone deacetylase (HDAC) inhibitor, has been approved for the treatment of epilepsy. Lacosamide 0-10 histone deacetylase 9 Homo sapiens 35-39 25931268-3 2015 The present investigation was designed to evaluate the effect of lacosamide on memory and brain HDAC levels. Lacosamide 65-75 histone deacetylase 9 Homo sapiens 96-100 25931268-10 2015 These results suggest that lacosamide at a 30mg/kg dose improves disrupted memory, possibly by inhibiting HDAC, and could be used to treat amnesic symptoms of Alzheimer"s disease. Lacosamide 27-37 histone deacetylase 9 Homo sapiens 106-110