PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28392905-0	2017	Cinnamaldehyde and eugenol change the expression folds of AKT1 and DKC1 genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study.	Eugenol	19-26	AKT serine/threonine kinase 1	Homo sapiens	58-62	
28915591-0	2017	Eugenol alleviated breast precancerous lesions through HER2/PI3K-AKT pathway-induced cell apoptosis and S-phase arrest.	Eugenol	0-7	AKT serine/threonine kinase 1	Homo sapiens	65-68	
28915591-7	2017	Furthermore eugenol for external (1 mg) markedly decreased the protein expressions of HER2 (62.9%), AKT (58.6%), PDK1 (56.4%), p85 (54.3%), Bcl2 (59.3%), NF-kappaB (65.7%), Bad (64.0%), Cyclin D1 (43.0%), while p21, p27 and Bax protein expressions were respectively increased 1.83-, 2.52- and 2.51-fold.	Eugenol	12-19	AKT serine/threonine kinase 1	Homo sapiens	100-103	
28915591-8	2017	The results showed eugenol could significantly inhibit the development of breast precancerous lesions by blocking HER2/PI3K-AKT signaling network.	Eugenol	19-26	AKT serine/threonine kinase 1	Homo sapiens	124-127	
29024500-10	2018	Finally, the expression levels of phosphate-Akt and MMP-2 in lung cancer cells were reduced after treatment with eugenol.	Eugenol	113-120	AKT serine/threonine kinase 1	Homo sapiens	44-47	
29024500-11	2018	CONCLUSION: Our results demonstrated the tumor suppressive roles of eugenol on lung cancer cell proliferation, migration, and invasion partially through the PI3K/Akt pathway and MMP activity in vitro.	Eugenol	68-75	AKT serine/threonine kinase 1	Homo sapiens	162-165	
34502165-0	2021	Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition.	Eugenol	0-7	AKT serine/threonine kinase 1	Homo sapiens	72-75	
34502165-9	2021	The protein levels of AKT serine/threonine kinase 1 (AKT), forkhead box O3 (FOXO3a), cyclin dependent kinase inhibitor 1A (p21), cyclin-dependent kinase inhibitor (p27), and Caspase-3 and -9 increased significantly in Eugenol-treated cells.	Eugenol	218-225	AKT serine/threonine kinase 1	Homo sapiens	22-51	
34502165-9	2021	The protein levels of AKT serine/threonine kinase 1 (AKT), forkhead box O3 (FOXO3a), cyclin dependent kinase inhibitor 1A (p21), cyclin-dependent kinase inhibitor (p27), and Caspase-3 and -9 increased significantly in Eugenol-treated cells.	Eugenol	218-225	AKT serine/threonine kinase 1	Homo sapiens	53-56