PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26434906-9 2015 CONCLUSIONS: Unlike capsaicin, eugenol could induce apoptosis both in presence and absence of functional p53. Eugenol 31-38 tumor protein p53 Homo sapiens 105-108 34840582-0 2021 A Metabolomic Investigation of Eugenol on Colorectal Cancer Cell Line HT-29 by Modifying the Expression of APC, p53, and KRAS Genes. Eugenol 31-38 tumor protein p53 Homo sapiens 112-115 34840582-5 2021 The purpose of this research was to investigate the anticancer effects of eugenol and variations in p53, KRAS, and APC gene expression and metabolic changes associated with the abovementioned gene expressions using 1HNMR spectroscopy. Eugenol 74-81 tumor protein p53 Homo sapiens 100-103 34840582-7 2021 After treating HT-29 cells with IC50 concentration of eugenol, RNA was extracted and cDNA was obtained from them and the expression of p53, KRAS, and APC genes was measured using the qRT-PCR technique. Eugenol 54-61 tumor protein p53 Homo sapiens 135-138 34840582-11 2021 The observed IC50 for eugenol was 500 muM, and the relative expression of APC and p53 genes in the treated cells increased compared to the control group, and the expression of KRAS oncogene gene decreased significantly. Eugenol 22-29 tumor protein p53 Homo sapiens 82-85 26434906-0 2015 Induction of Apoptosis by Eugenol and Capsaicin in Human Gastric Cancer AGS Cells--Elucidating the Role of p53. Eugenol 26-33 tumor protein p53 Homo sapiens 107-110 26434906-3 2015 The aim of the study was to elucidate the role of p53 in the induction of apoptosis by eugenol and capsaicin in a human gastric cancer cell line, AGS. Eugenol 87-94 tumor protein p53 Homo sapiens 50-53 15576237-7 2004 Interestingly, CYP2D6-treated eugenol strongly damaged C and G of the 5"-ACG-3" sequence complementary to codon 273 of the p53 gene. Eugenol 30-37 tumor protein p53 Homo sapiens 123-126 24330704-11 2013 Moreover, eugenol up-regulated the versatile cyclin-dependent kinase inhibitor p21WAF1 protein, and inhibited the proliferation of breast cancer cells in a p53-independent manner. Eugenol 10-17 tumor protein p53 Homo sapiens 156-159