PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16101137-8	2005	The regulatory effects of eugenol-related compounds on lipopolysaccharide (LPS)-induced cyclooxygenase-2 (COX-2) gene expression in RAW 264.7 cells were investigated by Northern blot analysis.	Eugenol	26-33	prostaglandin-endoperoxide synthase 2	Mus musculus	88-104	
29997055-2	2019	In lipopolysaccharide (LPS)-stimulated macrophages, eugenol reduces cyclooxygenase-2 expression, NF-kappaB activation, and inflammatory mediators.	Eugenol	52-59	prostaglandin-endoperoxide synthase 2	Mus musculus	68-84	
28882947-8	2017	The ability of methoxyphenols to inhibit LPS-stimulated Cox-2 gene expression declined in the order curcumin >> isoeugenol > bis-eugenol >> eugenol, and the rank of ability was related to their omega value.	Eugenol	121-128	prostaglandin-endoperoxide synthase 2	Mus musculus	56-61	
23160676-0	2012	Comparative inhibitory effects of magnolol, honokiol, eugenol and bis-eugenol on cyclooxygenase-2 expression and nuclear factor-kappa B activation in RAW264.7 macrophage-like cells stimulated with fimbriae of Porphyromonas gingivalis.	Eugenol	54-61	prostaglandin-endoperoxide synthase 2	Mus musculus	81-97	
16101137-8	2005	The regulatory effects of eugenol-related compounds on lipopolysaccharide (LPS)-induced cyclooxygenase-2 (COX-2) gene expression in RAW 264.7 cells were investigated by Northern blot analysis.	Eugenol	26-33	prostaglandin-endoperoxide synthase 2	Mus musculus	106-111	
12757841-0	2003	Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells.	Eugenol	0-7	prostaglandin-endoperoxide synthase 2	Mus musculus	19-35	
12757841-6	2003	In addition, eugenol suppressed the cyclooxygenase-2 (COX-2) gene expression in LPS-stimulated mouse macrophage cells.	Eugenol	13-20	prostaglandin-endoperoxide synthase 2	Mus musculus	36-52	
12757841-6	2003	In addition, eugenol suppressed the cyclooxygenase-2 (COX-2) gene expression in LPS-stimulated mouse macrophage cells.	Eugenol	13-20	prostaglandin-endoperoxide synthase 2	Mus musculus	54-59	
12757841-7	2003	On the line of COX-2 playing an important role in colon carcinogenesis further study was designed to investigate the effect of eugenol on the growth and COX-2 expression in HT-29 human colon cancer cells.	Eugenol	127-134	prostaglandin-endoperoxide synthase 2	Mus musculus	153-158	
12757841-8	2003	Eugenol inhibited the proliferation of HT-29 cells and the mRNA expression of COX-2, but not COX-1.	Eugenol	0-7	prostaglandin-endoperoxide synthase 2	Mus musculus	78-83	
12757841-9	2003	This result suggests that eugenol might be a plausible lead candidate for further developing the COX-2 inhibitor as an anti-inflammatory or cancer chemopreventive agent.	Eugenol	26-33	prostaglandin-endoperoxide synthase 2	Mus musculus	97-102