PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16123706-9	2005	Taken together, the activation of IL-6 and IL-8 mRNA gene expression may be one of the pathogenesis of zinc oxide-eugenol based and epoxy resin based root canal sealers-induced periapical inflammation.	Eugenol	114-121	C-X-C motif chemokine ligand 8	Homo sapiens	43-47	
23422489-2	2013	In the present study, we investigated the effect of eugenol on interleukin-8 (IL-8) production by IL-1beta-stimulated oral cells.	Eugenol	52-59	C-X-C motif chemokine ligand 8	Homo sapiens	63-76	
23422489-2	2013	In the present study, we investigated the effect of eugenol on interleukin-8 (IL-8) production by IL-1beta-stimulated oral cells.	Eugenol	52-59	C-X-C motif chemokine ligand 8	Homo sapiens	78-82	
23422489-8	2013	Eugenol (5-500 muM) significantly stimulated IL-8 production in HGF cells, but had bi-modal effects on HPCs, causing slight stimulation at lower concentration (5 muM) and a significant inhibition at higher concentration (500 muM), regardless of the presence or absence of serum.	Eugenol	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	45-49	
26960744-7	2016	Along with the lower levels of inflammatory cytokine gene expressions in the extract, treatment of the 2D IHOKs with Zn(2+) alone and treatment of the 3D IHOKs with Zn(2+) plus eugenol resulted in significantly lower expression levels of IL-1beta, IL-6, and IL-8 (P<0.05).	Eugenol	177-184	C-X-C motif chemokine ligand 8	Homo sapiens	258-262	
22946548-5	2012	In contrast, the pro-haptens eugenol, isoeugenol, and 2-aminophenol stimulated high levels of IL-8 release from neutrophils alone.	Eugenol	29-36	C-X-C motif chemokine ligand 8	Homo sapiens	94-98