PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35132703-0	2022	Eugenol restrains abdominal aortic aneurysm progression with down-regulations on NF-kappaB and COX-2.	Eugenol	0-7	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90	
35132703-7	2022	After elucidation the efficiency of eugenol against AAA progression by AAA diameter, hematoxylin-eosin staining and orcein staining, the down-regulations of eugenol on COX-2 and NF-kappaB were further detected by immunohistochemistry and western blot.	Eugenol	157-164	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	178-187	
35132703-9	2022	Excellent efficiency, high oral bioavailability and down-regulation on COX-2/NF-kappaB endowed eugenol great potential for future AAA therapy.	Eugenol	95-102	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	77-86	
20075264-1	2010	Eugenol, a methoxyphenol component of clove oil, suppresses cyclooxygenase-2 expression, while eugenol dimers prevent nuclear factor-kappaB (NF-kappaB) activation and inflammatory cytokine expression in lipopolysaccharide-stimulated macrophages.	Eugenol	95-102	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	141-150	
29126931-10	2018	Taken together, our findings suggest that allylguaiacol exerts a neuroprotective effect through the antioxidant activation and protein regulation of NF-kappaB p65 and DAXX-related signaling.	Eugenol	42-55	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	149-158	
25588851-0	2015	Antiasthmatic Effects of Eugenol in a Mouse Model of Allergic Asthma by Regulation of Vitamin D3 Upregulated Protein 1/NF-kappaB Pathway.	Eugenol	25-32	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	119-128	
33059262-0	2020	Anterior gradient 2 is a novel pro-tumor factor in pancreatic cancer under NF-kappaB subunit RelA trans-regulation that can be suppressed by eugenic acid.	Eugenol	141-153	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	75-84	
23160676-0	2012	Comparative inhibitory effects of magnolol, honokiol, eugenol and bis-eugenol on cyclooxygenase-2 expression and nuclear factor-kappa B activation in RAW264.7 macrophage-like cells stimulated with fimbriae of Porphyromonas gingivalis.	Eugenol	54-61	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	113-135	
23160676-10	2012	Both the fimbria-stimulated binding of NF-kappaB to its consensus sequence and phosphorylation-dependent proteolysis of inhibitor kappaB-alpha were markedly inhibited by magnilol and honokiol, whereas eugenol and bis-eugenol did not inhibit COX-2 expression and NF-kappaB activation.	Eugenol	201-208	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	39-48	
12963494-5	2003	We observed that bis-eugenol, but not eugenol, clearly inhibited the degradation of inhibitory kappa B-alpha in RAW264.7 murine macrophages stimulated with lipopolysaccharide and, consequently, the transcriptional activity of the stimulated NF-kappa B in the cells.	Eugenol	21-28	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	241-251	
17698059-8	2007	The isoeugenol analogues eugenol and allylbenzene also inhibited LPS-induced NF-kappaB signaling and iNOS expression, albeit with less potency than isoeugenol.	Eugenol	7-14	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	77-86