PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34677731-7	2021	Eugenol also reduced SARS-CoV-2 spike S1-induced activation of NF-kappaB and the expression of IL-6, IL-1beta and TNFalpha in human A549 lung cells.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	63-72	
28915591-7	2017	Furthermore eugenol for external (1 mg) markedly decreased the protein expressions of HER2 (62.9%), AKT (58.6%), PDK1 (56.4%), p85 (54.3%), Bcl2 (59.3%), NF-kappaB (65.7%), Bad (64.0%), Cyclin D1 (43.0%), while p21, p27 and Bax protein expressions were respectively increased 1.83-, 2.52- and 2.51-fold.	Eugenol	12-19	nuclear factor kappa B subunit 1	Homo sapiens	154-163	
17889685-0	2007	Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kappa B in human osteoblasts.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	72-94	
17889685-2	2007	In this study, the effects of eugenol on the activation of nuclear factor kappa B (NF-kappaB) and the expression of cyclooxygenase-2 (COX-2) in human osteoblasts were investigated.	Eugenol	30-37	nuclear factor kappa B subunit 1	Homo sapiens	59-81	
17889685-2	2007	In this study, the effects of eugenol on the activation of nuclear factor kappa B (NF-kappaB) and the expression of cyclooxygenase-2 (COX-2) in human osteoblasts were investigated.	Eugenol	30-37	nuclear factor kappa B subunit 1	Homo sapiens	83-92	
17889685-3	2007	The results showed that eugenol activated the nuclear translocation of NF-kappaB.	Eugenol	24-31	nuclear factor kappa B subunit 1	Homo sapiens	71-80	
35504091-0	2022	Eugenol suppresses the proliferation and invasion of TNF-alpha-induced fibroblast-like synoviocytes via regulating NF-kappaB and COX-2.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	115-124	
35504091-5	2022	Eugenol"s target genes were significantly associated with vascular endothelial growth factor (VEGF) and NF-kappaB (NF-kappaB) signaling pathway.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	104-113	
35504091-5	2022	Eugenol"s target genes were significantly associated with vascular endothelial growth factor (VEGF) and NF-kappaB (NF-kappaB) signaling pathway.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	115-124	
35504091-6	2022	Eugenol reversed the promoting effect of TNF-alpha on the expression of NF-kappaB signaling pathway-related proteins as well as prostaglandin-endoperoxide synthase 2 (PTGS2, also known as COX-2) protein.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	72-81	
35504091-8	2022	In conclusion, eugenol may represent a novel drug to suppress the progression of RA by inhibiting NF-kappaB signaling pathway and COX-2 expression in fibroblast-like synovial cells.	Eugenol	15-22	nuclear factor kappa B subunit 1	Homo sapiens	98-107	
30932261-0	2019	Eugenol inhibits non-small cell lung cancer by repressing expression of NF-kappaB-regulated TRIM59.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	72-81	
30932261-12	2019	Eugenol inhibited NSCLC via repression NF-kappaB-TRIM59 pathway.	Eugenol	0-7	nuclear factor kappa B subunit 1	Homo sapiens	39-48	
17889685-5	2007	Furthermore, the eugenol-modulated COX-2 expression was inhibited by an NF-kappaB inhibitor, N-acetylcysteine.	Eugenol	17-24	nuclear factor kappa B subunit 1	Homo sapiens	72-81	
17889685-6	2007	Taken together, eugenol might induce COX-2 expression through the activation of NF-kappaB in human osteoblasts.	Eugenol	16-23	nuclear factor kappa B subunit 1	Homo sapiens	80-89