PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20152883-2	2010	Eugenol possesses analgesic effects that may be related to the inhibition of voltage-dependent Na+ channels and/or to the activation of TRPV1 receptors or both.	Eugenol	0-7	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	136-141	
19376653-2	2009	Interestingly, eugenol shares several pharmacological actions with local anesthetics which include inhibition of voltage-gated sodium channel (VGSC) and activation of transient receptor potential vanilloid subtype 1 (TRPV1).	Eugenol	15-22	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	167-215	
19376653-2	2009	Interestingly, eugenol shares several pharmacological actions with local anesthetics which include inhibition of voltage-gated sodium channel (VGSC) and activation of transient receptor potential vanilloid subtype 1 (TRPV1).	Eugenol	15-22	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	217-222	
19376653-7	2009	At cellular level, eugenol reversibly inhibited APs and VGSCs in IB(4)+/TRPV1+/Na(v)1.8+ nociceptive TG neurons (Type I-Type III) and IB(4)-/TRPV1-/Na(v)1.8- nociceptive TG neurons (Type IV).	Eugenol	19-26	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	72-77	
19376653-7	2009	At cellular level, eugenol reversibly inhibited APs and VGSCs in IB(4)+/TRPV1+/Na(v)1.8+ nociceptive TG neurons (Type I-Type III) and IB(4)-/TRPV1-/Na(v)1.8- nociceptive TG neurons (Type IV).	Eugenol	19-26	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	141-146	
18543354-6	2008	The protective effect afforded by eugenol was significantly inhibited by prior administration of glibenclamide, the ATP-sensitive potassium (K(ATP)) channel blocker, but not by prior use of ruthenium red, the transient receptor potential vanilloid 1 (TRPV1) antagonist.	Eugenol	34-41	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	251-256	
16998128-7	2006	Our results demonstrated that eugenol inhibits I(Na) in a TRPV1-independent manner.	Eugenol	30-37	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	58-63	
9372790-12	1997	Our results suggest that eugenol activates a Ca(2+)-permeable ion channel in rat DRG neurons through two different mechanisms: a capsaicin receptor-mediated pathway and a pathway independent of the capsaicin-receptor.	Eugenol	25-32	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	198-216	
31570745-0	2019	Eugenol Reduces LDL Cholesterol and Hepatic Steatosis in Hypercholesterolemic Rats by Modulating TRPV1 Receptor.	Eugenol	0-7	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	97-102	
31570745-5	2019	Eugenol did not inhibit hepatic 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase but caused down-regulation of transient receptor potential vanilloid (TRPV1) channels in the liver.	Eugenol	0-7	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	154-159	
31570745-6	2019	Docking simulation using fast, rigid exhaustive docking (FRED) software indicated a tail-up/head-down interaction of eugenol with TRPV1 channel.	Eugenol	117-124	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	130-135	
31570745-7	2019	Data indicate that eugenol does not inhibit HMG-CoA reductase but rather induces its action by interaction with TRPV1 channels.	Eugenol	19-26	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	112-117