PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21656368-7 2011 Immunohistochemical analysis revealed that eugenol prevented the doxorubicin-induced activation of caspase-3 in cardiomyocytes. Eugenol 43-50 caspase 3 Rattus norvegicus 99-108 32089784-10 2020 However, treatment with eugenol resulted in a significant reduction (p < 0.01) in the levels of nitric oxide (NO) and 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, inhibited the activity of caspase-3, increased levels of Bcl-2 and significantly (p < 0.05) reduced levels of Bax protein, respectively, and also significantly (p < 0.05) increased the levels of SOD and GPx. Eugenol 24-31 caspase 3 Rattus norvegicus 191-200 30233696-8 2018 Western blot analysis demonstrated that the protein expression of cleaved Poly (ADP-ribose) polymerase 1, BAX and active caspase-3 in the eugenol group were significantly decreased, while B-cell lymphoma 2 expression was significantly increased compared with the control group (P<0.05). Eugenol 138-145 caspase 3 Rattus norvegicus 121-130