PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15210026-3	2004	The aim of this work was to test the effect of zinc released from zinc oxide-eugenol (ZOE) cements, on the activity of the major pulpal gelatinolytic MMPs.	Eugenol	77-84	matrix metallopeptidase 2	Homo sapiens	150-154	
18291278-4	2008	The aim of this study was to investigate the effects of epoxy resin-based root canal sealer AH26 and zinc oxide-eugenol-based root canal sealer Canals and one paste sealer N2 on the expression of MMPs and PAs in human osteoblastic cell line U2OS cells.	Eugenol	112-119	matrix metallopeptidase 2	Homo sapiens	196-200	
30518369-7	2018	Real-time PCR was used to study the effect of eugenol on the expression of anti-metastatic genes such as MMP2, MMP9, and TIMP-1, and genes involved in apoptosis including Caspase3, Caspase7, and Caspase9.	Eugenol	46-53	matrix metallopeptidase 2	Homo sapiens	105-109	
30518369-9	2018	Eugenol-treated cells showed significantly decreased MMP2 and MMP9 expression and an insignificant increase in TIMP1 expression in HER2 positive and triple negative breast cancer cells.	Eugenol	0-7	matrix metallopeptidase 2	Homo sapiens	53-57	
29024500-10	2018	Finally, the expression levels of phosphate-Akt and MMP-2 in lung cancer cells were reduced after treatment with eugenol.	Eugenol	113-120	matrix metallopeptidase 2	Homo sapiens	52-57	
29024500-11	2018	CONCLUSION: Our results demonstrated the tumor suppressive roles of eugenol on lung cancer cell proliferation, migration, and invasion partially through the PI3K/Akt pathway and MMP activity in vitro.	Eugenol	68-75	matrix metallopeptidase 2	Homo sapiens	178-181