PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16039848-1 2005 The inhibition of the last human carbonic anhydrase (CA, EC 4.2.1.1) isozyme (hCA XIV) discovered has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and zonisamide), as well as the sulfamate antiepileptic drug topiramate. Zonisamide 303-313 carbonic anhydrase 14 Homo sapiens 78-85