PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10982153-5 2000 The IFN-gamma production of CLN lymphocytes as measured by ELISA method was markedly impaired in the early stage of tumor-bearing mice treated with phenytoin or zonisamide, and the median survival time (MST) of controls and of mice treated with either phenytoin or zonisamide was 13, 10 and 11 days, respectively, which was not a statistically significant difference. Zonisamide 161-171 interferon gamma Mus musculus 4-13 10982153-5 2000 The IFN-gamma production of CLN lymphocytes as measured by ELISA method was markedly impaired in the early stage of tumor-bearing mice treated with phenytoin or zonisamide, and the median survival time (MST) of controls and of mice treated with either phenytoin or zonisamide was 13, 10 and 11 days, respectively, which was not a statistically significant difference. Zonisamide 265-275 interferon gamma Mus musculus 4-13 10982153-8 2000 Two anticonvulsants, phenytoin and zonisamide, showed a significant inhibitory effect on IFN-gamma production by CLN lymphocytes in murine glioma models, although there was no statistically significant difference in MST between controls and the anticonvulsant-treated mice. Zonisamide 35-45 interferon gamma Mus musculus 89-98