PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35514993-0	2022	Oleamide-Mediated Polarization of M1 Macrophages and IL-1beta Production by Regulating NLRP3-Inflammasome Activation in Primary Human Monocyte-Derived Macrophages.	oleylamide	0-8	interleukin 1 alpha	Homo sapiens	53-61	
35514993-7	2022	Results showed that oleamide promoted naive macrophages (M0) toward the M1 phenotype by upregulating M1-associated genes (IL-1beta, iNOS, CXCL10), along with downregulation of M2-associated genes (Arg-1, CD206, CCL22).	oleylamide	20-28	interleukin 1 alpha	Homo sapiens	122-130	
35514993-10	2022	Whether oleamide functioned as a second signal that activated the NLRP3 inflammasome and mediated IL-1beta production was further investigated using LPS-primed MDMs followed by oleamide treatment that induced activation of inflammasome-related proteins including NLRP3, ASC, cleaved casp-1, and cleaved IL-1beta.	oleylamide	8-16	interleukin 1 alpha	Homo sapiens	98-106	
35514993-10	2022	Whether oleamide functioned as a second signal that activated the NLRP3 inflammasome and mediated IL-1beta production was further investigated using LPS-primed MDMs followed by oleamide treatment that induced activation of inflammasome-related proteins including NLRP3, ASC, cleaved casp-1, and cleaved IL-1beta.	oleylamide	8-16	interleukin 1 alpha	Homo sapiens	303-311	
35514993-10	2022	Whether oleamide functioned as a second signal that activated the NLRP3 inflammasome and mediated IL-1beta production was further investigated using LPS-primed MDMs followed by oleamide treatment that induced activation of inflammasome-related proteins including NLRP3, ASC, cleaved casp-1, and cleaved IL-1beta.	oleylamide	177-185	interleukin 1 alpha	Homo sapiens	98-106	
35514993-11	2022	These findings suggested that oleamide promoted M1 macrophage polarization and increased IL-1beta production by activating the NLRP3 inflammasome in primary MDMs.	oleylamide	30-38	interleukin 1 alpha	Homo sapiens	89-97