PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27590241-7 2016 Moreover, intracellular Ang II (100 nM), by itself, reduced the potassium current, an effect decreased by intracellular valsartan (100 nM). Valsartan 120-129 angiogenin Rattus norvegicus 24-27 27590241-8 2016 Valsartan (10-9 M) dialyzed into the cell abolished the effect of Ang-(1-12) (100 nM). Valsartan 0-9 angiogenin Rattus norvegicus 66-69 23141017-8 2012 (4) Valsartan not only attenuated the proliferation of VSMC and the intimal thickening but also upregulated the expression of ACE2 and the level of Ang(1-7) and downregulated the expression of AT(1)R and the level of AngII, p-ERK in this model. Valsartan 4-13 angiogenin Rattus norvegicus 148-155 26887263-11 2015 Pre-treatment with Valsartan, TCS HDAC6 20b or Ac-SDKP could inhibited all this changes induced by Ang II in vitro. Valsartan 19-28 angiogenin Rattus norvegicus 99-102 23141017-9 2012 CONCLUSION: Intimal thickening after balloon injury is linked with reduced expression of ACE2.Valsartan can inhibit the intimal thickening possibly by upregulating ACE2 and Ang(1-7) and downregulating AT(1) in this model. Valsartan 94-103 angiogenin Rattus norvegicus 173-180 12895663-7 2003 The reduced metabolism of Ang III may prolong its half-life in valsartan-treated animals. Valsartan 63-72 angiogenin Rattus norvegicus 26-29 21056585-7 2011 KEY FINDINGS: In the presence of AT(1)-antagonist valsartan, Ang II induced vasodilatation, which was more pronounced in the arteries incubated with Ile-Pro-Pro (P<0.05) compared to the other compounds. Valsartan 50-59 angiogenin Rattus norvegicus 61-64 16220196-15 2005 Valsartan and PD98059 blocked Ang II-stimulated ERK activation. Valsartan 0-9 angiogenin Rattus norvegicus 30-33 18619357-11 2008 If tanshinone II or valsartan was added to the culture medium before Ang II, both of them could inhibit the increase of c-fos, c-jun mRNA expression (P < 0.01), cardiomyocyte protein synthesis rate (P < 0.01), and cardiomyocyte size (P < 0.05) induced by Ang II. Valsartan 20-29 angiogenin Rattus norvegicus 69-72 16940708-9 2006 An MTS assay revealed that Ang II treatment significantly decreased the functional activity in BM-EPCs, and this effect was significantly reversed by valsartan. Valsartan 150-159 angiogenin Rattus norvegicus 27-30