PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27474278-6	2016	The PNIPAAm chains could extend and shrink with different temperature, which suggested that PNIPAAm on the surface of gold nanoparticles could regulate interaction between thrombin and aptamer according to temperature changing.	poly-N-isopropylacrylamide	4-11	coagulation factor II, thrombin	Homo sapiens	172-180	
27474278-6	2016	The PNIPAAm chains could extend and shrink with different temperature, which suggested that PNIPAAm on the surface of gold nanoparticles could regulate interaction between thrombin and aptamer according to temperature changing.	poly-N-isopropylacrylamide	92-99	coagulation factor II, thrombin	Homo sapiens	172-180	
27474278-7	2016	At 25 C, PNIPAAm was hydrophilic extended state, which blocked the interaction between thrombin and aptamer on the surface of gold nanoparticles, therefore thrombin activity had no change.	poly-N-isopropylacrylamide	9-16	coagulation factor II, thrombin	Homo sapiens	87-95	
27474278-7	2016	At 25 C, PNIPAAm was hydrophilic extended state, which blocked the interaction between thrombin and aptamer on the surface of gold nanoparticles, therefore thrombin activity had no change.	poly-N-isopropylacrylamide	9-16	coagulation factor II, thrombin	Homo sapiens	156-164	
27474278-8	2016	On the contrary, at 37 C, PNIPAAm transformed from hydrophilic extended state to hydrophobic shrank state, allowing the aptamer to capture thrombin, inhibiting the activity of thrombin.	poly-N-isopropylacrylamide	26-33	coagulation factor II, thrombin	Homo sapiens	139-147	
27474278-8	2016	On the contrary, at 37 C, PNIPAAm transformed from hydrophilic extended state to hydrophobic shrank state, allowing the aptamer to capture thrombin, inhibiting the activity of thrombin.	poly-N-isopropylacrylamide	26-33	coagulation factor II, thrombin	Homo sapiens	176-184